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April 1, 2021Archives of Iranian Medicine20 citationsOpen Access

Levels and Trends of Hypertension at National and Subnational Scale in Iran from 1990 to 2016: A Systematic Review and Pooled Analysis

SSSadaf G SepanlouPMParinaz MehdipourAGAli Ghanbari

Key Result

From 1990 to 2016, the age-standardized prevalence of hypertension in Iran increased from 8.7% to 28.8% in women and from 8.0% to 24.2% in men.

Study Design

Type

Systematic Review

Multicenter

Yes

Structured PICO

P
Population
Systematic review and pooled analysis of population-based studies and national surveys to estimate trends in hypertension prevalence among adults in Iran from 1990 to 2016.
O
Outcome
Mean systolic and diastolic blood pressure, and prevalence of hypertension by sex, age, province, and yearsurrogate

The prevalence of hypertension in Iran has increased dramatically from 1990 to 2016, highlighting a growing public health challenge that threatens the achievement of global health targets.

Abstract

BACKGROUND: Raised blood pressure is a serious risk factor for several non-communicable diseases (NCDs) in Iran. In this study, we aimed to estimate the mean of systolic blood pressure (SBP) and diastolic blood pressure (DBP) and subsequently, the prevalence of hypertension by sex, age, province, and year in Iran. METHODS: We conducted a systematic review using PubMed, Web of Science, and Scopus databases through December 2017. We also used individual level data from eight national surveys, aggregated data from seven subnational population-based studies, and extracted data reported in 52 published studies. We used a two-stage model including Age-Spatio-Temporal and Gaussian process regression (GPR) to estimate mean systolic and diastolic blood pressure and used a crosswalk model to estimate the prevalence of hypertension by sex, age, province, and year. RESULTS: The number of hypertensive adults increased in Iran from 1.8 million (882 thousand in women) in 1990 to 13.6 million (7.2 million in women) in 2016. The national age-standardized prevalence of hypertension increased from 8.7% (7.8-9.7) to 28.8% (27.7-30.0) in women and from 8.0% (7.2-8.9) to 24.2% (23.1-25.3) in men from 1990 to 2016. Mean systolic and diastolic blood pressures show a similar increasing trend. CONCLUSION: During the past 27 years, we observed an increase in the age-standardized prevalence and mean levels of blood pressure. If the current trend in levels of blood pressure and prevalence of hypertension continue in the coming years, Iran will not achieve the sixth target of the Global Action Plan by 2020 and the Sustainable Development Goals (SDGs) by 2030.

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Cite This Study

Sepanlou et al. (2021) conducted a systematic review in Hypertension. Time period (1990 to 2016) vs. 1990 baseline was evaluated on Age-standardized prevalence of hypertension. From 1990 to 2016, the age-standardized prevalence of hypertension in Iran increased from 8.7% to 28.8% in women and from 8.0% to 24.2% in men.

synapsesocial.com/papers/6a635f574f5ef41b946ac2dahttps://doi.org/10.34172/aim.2021.43
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