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April 17, 2001Angewandte Chemie International Edition166 citations

Dual-Signaling Fluorescent Chemosensors Based on Conformational Restriction and Induced Charge Transfer

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JMJesse V. MelloNFNathaniel S. Finney

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Abstract

Twist and shout! By restricting conformation, 2,6-biarylpyridines can be induced to “speak” to us through increased fluorescence emission. In combination with induced charge transfer, this allows these simple fluorophores to reveal otherwise silent binding events to alkali metal and alkaline earth cations through brightening and color change (see picture; from left to right: no metal, Li+, Mg2+, and Ca2+).

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Mello et al. (2001) studied this question.

synapsesocial.com/papers/6a63fedeb5b214049b7a865fhttps://doi.org/10.1002/1521-3773(20010417)40:8<1536::aid-anie1536>3.0.co;2-r
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