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February 1, 2000Blood259 citations

CREB-binding protein and p300: molecular integrators of hematopoietic transcription

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GBGerd A. Blobel

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Abstract

Differentiation of pluripotent hematopoietic stem cells into mature circulating blood cells is coordinated by a complex series of transcriptional events. During the last decade, numerous transcription factors have been identified whose expression is highly lineage-restricted within the hematopoietic

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Gerd A. Blobel (2000) studied this question.

synapsesocial.com/papers/6a6522957a97fa27bd57e3a2https://doi.org/10.1182/blood.v95.3.745.003k05_745_755
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Core histone hyperacetylation co‐maps with generalized DNase I sensitivity in the chicken beta‐globin chromosomal domain.1994 · 542 citations
  2. 2CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis (Review).1998 · 92 citations
  3. 3Acetylation of HMG I(Y) by CBP Turns off IFNβ Expression by Disrupting the Enhanceosome1998 · 321 citations
  4. 4Requirement of an E1A-sensitive Coactivator for Long-range Transactivation by the β-Globin Locus Control Region1999 · 47 citations
  5. 5The p300/CBP family: integrating signals with transcription factors and chromatin1997 · 490 citations