Renal sinus fat volume was independently associated with higher systolic blood pressure (B = 0.746) and diastolic blood pressure in obese individuals with hypertension.
Cross-Sectional (n=51)
No
Is renal sinus fat associated with metabolic parameters and blood pressure control in obese individuals with hypertension?
Renal sinus fat volume is independently associated with higher blood pressure and central fat accumulation in obese hypertensive patients, suggesting a potential role in metabolic disorders.
Effect estimate: B = 0.746 (95% CI 0.387-1.104)
p-value: p=<0.001
Abstract Renal sinus fat (RSF) crucially influences metabolic regulation, inflammation, and vascular function. We investigated the association between RSF accumulation, metabolic disorders, and nutritional status in obese individuals with hypertension. A cross-sectional study involved 51 obese hypertensive patients from Salamat Specialized Community Clinic (February–September 2022). Basic and clinical information were collected through interviews. Data included anthropometrics, blood pressure, number of antihypertensive medications, body composition (bioelectrical impedance analysis), dietary intake (semi-quantitative 147-item food frequency questionnaire), and blood samples. Renal sinus fat was measured via ultrasonography. Statistical analyses included Pearson correlation, binary logistic regression, and linear regression. RSF positively correlated with abdominal visceral adipose tissue (VAT) area ( P = 0.016), systolic blood pressure (SBP) ( P = 0.004), and diastolic blood pressure (DBP) ( P = 0.005). A strong trend toward a positive association was observed between antihypertensive medications and RSF ( P = 0.062). In linear regression, RSF was independently associated with abdominal VAT area, SBP, and DBP after adjusting for confounders. After considering other risk factors, RSF volume relates to prescribed antihypertensive medications, hypertension, and central fat accumulation in obese hypertensive subjects. These findings suggest the need for further investigations into whether RSF promotes metabolic disorders.
Anvarifard et al. (2024) conducted a cross-sectional in Obesity and Hypertension (n=51). Renal sinus fat (RSF) was evaluated on Systolic blood pressure (SBP) (B = 0.746, 95% CI 0.387-1.104, p=<0.001). Renal sinus fat volume was independently associated with higher systolic blood pressure (B = 0.746) and diastolic blood pressure in obese individuals with hypertension.