Pacemapping and activation mapping provided similar localizing information with modest spatial resolution, as pacemap concordance significantly decreased with increasing distance from the origin (P<0.01).
Observational (n=15)
Does pacemapping provide similar spatial resolution to activation mapping for localizing idiopathic right ventricular outflow tract tachycardia?
Pacemapping and activation mapping provide similar but modest spatial resolution for localizing RVOT tachycardia, which can be optimized using 3D electroanatomical mapping.
p-value: p=<0.01
BACKGROUND: The purpose of this study was to compare the spatial resolution of activation mapping and pacemapping in patients undergoing ablation of idiopathic ventricular tachycardia (VT) arising from the right ventricular outflow tract (RVOT). A direct comparison of the two techniques has not been undertaken. METHODS AND RESULTS: Electroanatomical activation maps of the RVOT were obtained during VT in 15 patients. Pacemaps were obtained from multiple sites, tagged on the activation map, and scored according the degree of concordance between the paced QRS configuration and that of VT. The site of successful ablation was considered the VT site of origin. Initial endocardial activation away from the site of origin was rapid; the mean area of myocardium activated within the first 10 msec (early activation area, EAA) was 3.0 +/- 1.6 cm(2) (range: 1.3-6.4 cm(2)). Best pacemap scores were always obtained adjacent to the site of origin. Pacemap concordance, and the probability of an exact pacemap match significantly decreased with increasing distance of the pacing site from the site of origin (P < 0.01). All patients had more than one pacing site yielding a best pacemap score. The greatest distance between such sites in an individual patient ranged from 11 to 26 mm (mean: 18 +/- 5 mm), and was strongly correlated with the size of the EAA (r = 0.77, P < 0.001). CONCLUSIONS: Pacemapping and activation mapping provide similar localizing information. The spatial resolution of each technique is modest, varies between patients, and may be optimized by three-dimensional data display.
Azegami et al. (2005) conducted an observational in Idiopathic right ventricular outflow tract tachycardia (n=15). Pacemapping and activation mapping was evaluated on Spatial resolution (pacemap concordance and distance from site of origin) (p=<0.01). Pacemapping and activation mapping provided similar localizing information with modest spatial resolution, as pacemap concordance significantly decreased with increasing distance from the origin (P<0.01).