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November 18, 2005Infection and Immunity150 citationsOpen Access

Membrane Cholesterol: a Crucial Molecule Affecting Interactions of Microbial Pathogens with Mammalian Cells

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PGPawel GoluszkoBNB. Nowicki

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Abstract

Cholesterol, which is required for viability and cell proliferation, is a major sterol of mammalian cells. More than 90% of cellular cholesterol is located at the plasma membrane. Several microorganisms and bacterial products target lipid rafts, membrane microdomains of eukaryotic cells enriched in

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Goluszko et al. (2005) studied this question.

synapsesocial.com/papers/6a6c3c2947a1bfb288f37638https://doi.org/10.1128/iai.73.12.7791-7796.2005
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