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The first edition of this already standard text of gastroenterology appeared in 1991. Changes in biology and clinical practice fully support this new edition. This text is different and uniquely strong in its integration of the scientific basis of gastroenterology into all sections and is particularly appropriate for those under age 40 in using the molecular biology they learned in medical school. Those of us over 40 must catch up with the new biology to comprehend pathogenesis and treatment. The first part of the book, some 600 pages and 26 chapters, reviews all the pertinent science on general topics, such as gastrointestinal hormones, epithelia, motility, and electrolyte secretion. These chapters feature frequent tables, schemas of relationships, and understandable cartoons incorporating a wealth of information, rendering comprehensible complex, new, and highly important systems. The second part, some 500 pages and also 26 chapters, moves through the gastrointestinal tract with the approach
Frank L. Iber (1996) studied this question.