The authors argue that the obesity paradox in chronic heart failure is a real phenomenon supported by overwhelming data, requiring careful consideration of clinical messages for patients.
The obesity paradox in chronic heart failure (HF) has a number of facets that require discussion. These involve beliefs, various statistical results, and clinical messages. We believe that the paradox is here to stay—the data are just too overwhelming for us to believe otherwise. The main question, however, is what should be the message for patients and their physicians? Clinical Pharmacology & Therapeutics (2011) 90 1, 188–190. doi:10.1038/clpt.2011.72
Anker et al. (2011) studied this question.
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