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Synapse
March 31, 2006Molecular and Cellular Biology132 citationsOpen Access

Multiple Functions of the Integrin α6β4 in Epidermal Homeostasis and Tumorigenesis

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KWKevin WilhelmsenSLSandy H.M. LitjensASArnoud Sonnenberg

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Abstract

Since the discovery of the α6β4 integrin in the late 1980s, our understanding of its role in providing stable adhesion of epithelial cells to basement membranes (BM) has significantly increased. α6...

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Cite This Study

Wilhelmsen et al. (2006) studied this question.

synapsesocial.com/papers/6a6ffa5e6c240de38cdba41dhttps://doi.org/10.1128/mcb.26.8.2877-2886.2006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin.1995 · 137 citations
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  3. 3Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain1998 · 197 citations
  4. 4Deletion of a Cytoplasmic Domain of Integrin β4 Causes Epidermolysis Bullosa Simplex12002 · 74 citations
  5. 5Integrin α6β4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells2005 · 112 citations