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November 1, 1992Annual Review of Cell Biology298 citations

Actin Filaments, Stereocilia, and Hair Cells: How Cells Count and Measure

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LTL G TilneyMTM S TilneyDDDavid J. DeRosier

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Abstract

INTRODUCTION 257 OBSERVATIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 Stage i-Pre 8 Day Embryos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 Stage 2-Embryos 8-12 Days . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 Stage 3-Embryos 13-16 Days . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 Stage 4-Embryos i7 Days and Older ......... . .... ..... 265 CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 How Does the Pattern Develop? . . ... . ... . .... .... .... . .. . . ... . . .... .. 266 How Do Cells Get Assembly Information? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 Influences External to the Cochlea Proper Help Regulate Assembly . . . . . . . . . . . . 269 How Cells Count and Measure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . 27 1 Cells Build Complex Structures Step Upon Step . . . . . . . . . . . . . . . . . . . . . . . . . . . 272

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Tilney et al. (1992) studied this question.

synapsesocial.com/papers/6a70d37d26a7f98052dd4835https://doi.org/10.1146/annurev.cb.08.110192.001353
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