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February 20, 2008Bosnian Journal of Basic Medical Sciences3 citationsOpen Access

Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases

ĐSĐemo SubašićJKJasenko KaramehićFLFarid Ljuca

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Abstract

Diagnosis and management of patients with SLE (Systemic Lupus Eritematosus), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), involves specific diagnostic tests, such as IFA-AMA, IFA anti-dsDNA and immunoblotting for the detection of autoantibodies for specific autoantigens (mitochondria, dsDNA, M2, LKM-1, LC-1, SLA/LP). We established specific correlation between the detected autoantibodies and corresponding clinical findings. The total of 813 serum specimens were probed with IFA-anti-dsDNA, 98 of which tested positive. We also performed dilution analysis to the end point for all the positive specimens. Numerous specimens were tested by IFA, AMA and immunoblotting.

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Cite This Study

Subašić et al. (2008) studied this question.

synapsesocial.com/papers/6a7313810e01f79bdbcd5be4https://doi.org/10.17305/bjbms.2008.3004
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