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July 22, 2016Cell Research336 citationsOpen Access

The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death

ILIdo LivnehVCVictoria Cohen‐KaplanCCChen Cohen-Rosenzweig

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Abstract

The 26S proteasome is a large, ∼2.5 MDa, multi-catalytic ATP-dependent protease complex that serves as the degrading arm of the ubiquitin system, which is the major pathway for regulated degradation of cytosolic, nuclear and membrane proteins in all eukaryotic organisms.

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Cite This Study

Livneh et al. (2016) studied this question.

synapsesocial.com/papers/6a73d09776f4fb0e4269f0c7https://doi.org/10.1038/cr.2016.86
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