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April 1, 1988Pacing and Clinical Electrophysiology30 citations

Sudden Death Associated with Alcohol Consumption

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RPRalph J. PanosFSFrederick J. SuttonPYPaul J. Young-Hyman

Structured PICO

Does intravenous ethanol infusion induce ventricular arrhythmias in survivors of cardiac arrest associated with binge drinking?

P
Population
1 binge drinker who survived sudden cardiac arrest after heavy beer consumption, with no clinically detectable heart disease.
I
Intervention
Intravenous ethanol infusion during electrophysiological testing
C
Comparator
Electrophysiological testing without alcohol infusion (baseline and 24 hours later)
O
Outcome
Induction of ventricular tachycardiasurrogate

Alcohol consumption can trigger lethal ventricular arrhythmias in susceptible individuals, and alcohol challenge during EP testing may help identify this risk in survivors of unexplained cardiac arrest.

Abstract

Evaluation of a binge drinker who died suddenly after a weekend of heavy beer consumption, and had been resuscitated successfully, revealed no evidence of clinically detectable heart disease. Baseline electrophysiological testing was normal. Following intravenous ethanol infusion, paired ventricular extrastimuli from the right ventricle induced a rapid polymorphic ventricular tachycardia requiring cardioversion. Repeat electrophysiological testing 24 hours later without alcohol infusion was again normal. The patient was discharged on no medications and was instructed to refrain from drinking alcohol. Approximately 3 months later the patient died suddenly after heavy beer consumption. Alcohol should be considered in the evaluation of survivors of cardiac arrest and alcohol challenge may be useful in their evaluation.

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Cite This Study

Panos et al. (1988) studied this question.

synapsesocial.com/papers/6a73f6b5fe94123d791ee7cdhttps://doi.org/10.1111/j.1540-8159.1988.tb06002.x
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