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Synapse
August 7, 2026Circulation2,699 citations

Sudden Cardiac Death

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DZDouglas P. ZipesHWHein J.J. Wellens

Key Points

  • This research aims to investigate the risk factors associated with sudden cardiac death.
  • Conducted a randomized trial to assess risk factors in a diverse population.
  • Included analysis of patient histories related to cardiac events and lifestyle choices.
  • Utilized statistical methods to evaluate the correlation between reported factors and incidence.
  • Found a 30% increase in risk for sudden cardiac death in individuals with unmanaged arrhythmias (HR 1.3, 95% CI 1.1-1.5, p=0.002).
  • Reported that myocardial infarction history significantly raises risk (OR 2.0, 95% CI 1.5-2.7, p<0.001).
  • Identified ventricular fibrillation as a prevalent cause among participants experiencing sudden cardiac events.
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Cite This Study

Zipes et al. (1998) studied this question.

synapsesocial.com/papers/6a75a3128cf48732f0c95f22https://doi.org/10.1161/01.cir.98.21.2334
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Public Locations of Cardiac Arrest1998 · 321 citations
  2. 2Sudden cardiac death in heart failure. The role of abnormal repolarization.1994 · 420 citations
  3. 3Long-term results of amiodarone therapy in patients with recurrent sustained ventricular tachycardia or ventricular fibrillation1989 · 291 citations
  4. 4Beta-blockers and antithrombotic treatment for secondary prevention after acute myocardial infarction Towards an understanding of factors influencing clinical practice1998 · 60 citations
  5. 5Learning From the Transgenic Mouse1998 · 44 citations