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March 30, 2020Infection and Immunity18 citationsOpen Access

Mice Lacking γδ T Cells Exhibit Impaired Clearance of Pseudomonas aeruginosa Lung Infection and Excessive Production of Inflammatory Cytokines

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TOToka OmarPZPascal ZiltenerECErin Chamberlain

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Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic and life-threatening infections in immunocompromised patients. A better understanding of the role that innate immunity plays in the control of P. aeruginosa infection is crucial for therapeutic development. Specifically, the role of unconventional immune cells like γδ T cells in the clearance of P. aeruginosa lung infection is not yet well characterized.

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Omar et al. (2020) studied this question.

synapsesocial.com/papers/6a777850d3a6aa87c6bdc6aahttps://doi.org/10.1128/iai.00171-20
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