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September 23, 2004Journal of the American Chemical Society141 citations

Isothermal Titration Calorimetry Studies on the Binding of DNA Bases and PNA Base Monomers to Gold Nanoparticles

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AGA. GourishankarSSSourabh ShuklaKGKrishna N. Ganesh

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Abstract

An isothermal titration calorimetric (ITC) investigation of the interaction of DNA bases and PNA base monomers with gold nanoparticles is described revealing a binding sequence in the order C > G > A > T. Direct measurement of the strength of interaction of ligands with nanogold by ITC has important implications in surface modification strategies for biomedical, catalysis, and nanoarchitecture applications.

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Cite This Study

Gourishankar et al. (2004) studied this question.

synapsesocial.com/papers/6a79f38f4c448619ca0df343https://doi.org/10.1021/ja046785g
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