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May 1, 1989Antimicrobial Agents and Chemotherapy54 citationsOpen Access

Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection

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SHS.C. HarrisJWJack WallaceGFGeorge Foulds

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Abstract

A megabore column gas-liquid chromatographic method which uses nitrogen-phosphorus detection was developed for the analysis of fluconazole in plasma, serum, cerebrospinal fluid, or urine. The assay was linear from 0.2 to 200 micrograms/ml and had an average coefficient of variation of 7%. The suitability of the assay for pharmacokinetic studies was demonstrated.

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Harris et al. (1989) studied this question.

synapsesocial.com/papers/6a7f63ae731936e168a72eddhttps://doi.org/10.1128/aac.33.5.714
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