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July 15, 1992Journal of the American Veterinary Medical Association62 citationsOpen Access

Clinical findings in cats with dilated cardiomyopathy and relationship of findings to taurine deficiency

PPPaul D. PionMKMark D. KittlesonWTWilliam P. Thomas

Structured PICO

P
Population
70 cats with moderate to severe idiopathic myocardial failure (dilated cardiomyopathy), including 37 evaluated prospectively (1986-1988) and 33 studied retrospectively (1980-1986).
O
Outcome
Clinical findings, plasma taurine concentration, and diet history

Most cases of dilated cardiomyopathy in cats are caused by diet-induced taurine deficiency and are therefore preventable.

Abstract

Summary Between October 1986 and September 1988, 37 cats with moderate to severe idiopathic myocardial failure (dilated cardiomyopathy) were evaluated prospectively. Low plasma taurine concentration and diet history including foods that can cause taurine deficiency were documented in most of the cats. Comparison with a retrospectively studied population of 33 cats with dilated cardiomyopathy diagnosed between 1980 and 1986 demonstrated that the clinical and historical findings in the 33 retrospectively studied cats were similar to those in the 37 cats studied prospectively. Clinical findings in the 2 groups were also similar to findings previously reported in the literature. Because clinical findings and diet history were similar in the prospective and retrospective groups, we believe that many cats in the latter group had diet-induced taurine deficiency. These findings support the conclusion that most cases of dilated cardiomyopathy in cats have a common etiopathogenesis related to diet and as such are preventable.

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Cite This Study

Pion et al. (1992) studied this question.

synapsesocial.com/papers/6a8196b30be7de9fdeb955c6https://doi.org/10.2460/javma.1992.201.02.267
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