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April 21, 2009Interactive Cardiovascular and Thoracic Surgery13 citationsOpen Access

Transpulmonary versus continuous thermodilution cardiac output after valvular and coronary artery surgery

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RBR. -M. B. G. E. BreukersAGA. B. Johan GroeneveldRWRob B. P. de Wilde

Key Result

Transpulmonary thermodilution cardiac output correlated with continuous right-sided thermodilution after valvular (r=0.64, P<0.001) and coronary artery surgery (r=0.81, P<0.001).

Study Design

Type

Observational (n=16)

Structured PICO

Does transpulmonary thermodilution cardiac output measurement correlate with continuous right-sided thermodilution in patients after valvular and coronary artery surgery?

P
Population
16 ICU patients with pulmonary and femoral artery catheters after valvular (n=8) or coronary artery (n=8) surgery undergoing fluid loading steps.
E
Exposure
Transpulmonary thermodilution cardiac output (COtp) measurement
C
Comparator
Continuous right-sided thermodilution technique (CCO)
O
Outcome
Correlation between COtp and CCO measurements and their fluid-induced changessurrogate

Transpulmonary thermodilution and continuous right-sided thermodilution are of similar value in predicting and monitoring fluid responses after cardiac surgery, suggesting left-sided valvular insufficiencies do not significantly confound transpulmonary measurements.

Main Result

Effect estimate: r=0.64 (valvular) and r=0.81 (coronary)

p-value: p=<0.001

Abstract

Residual left-sided valvular insufficiencies after valvular surgery may confound transpulmonary thermodilution cardiac output (COtp). We compared the technique with the continuous right-sided thermodilution technique (CCO) after valvular surgery (n=8) and coronary artery surgery (n=8). Patients with pulmonary and femoral artery catheters in the intensive care unit (ICU) were included. After valvular surgery, there was minimal aortic insufficiency in four patients and minimal to moderate mitral valve insufficiency in six. Five fluid loading steps (250 ml) were done in each patient. CCO and COtp were measured prior to and 15 min after each step. The cardiac output was lower after valvular than coronary artery surgery but responses to fluid loading steps were similar among surgery types and techniques. After valvular and coronary artery surgery, cardiac output was lower prior to responses than in non-responses to fluids, by either technique. After valvular surgery, COtp and CCO correlated (r=0.64, P<0.001, n=48) but fluid-induced changes did not. After coronary artery surgery, COtp and CCO correlated (r=0.81, P<0.001) and changes also did (r=0.55, P<0.001). At fluid-induced CCO increases <20%, the r for changes in cardiac output measured by both techniques was similar after valvular and coronary artery surgery. Thus, COtp and CCO were of similar value in predicting and monitoring fluid responses after both surgery types. This argues against left-sided valvular insufficiencies confounding COtp.

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Cite This Study

Breukers et al. (2009) conducted an observational in Post-valvular and coronary artery surgery (n=16). Transpulmonary thermodilution cardiac output (COtp) vs. Continuous right-sided thermodilution technique (CCO) was evaluated on Correlation between COtp and CCO (r=0.64 (valvular) and r=0.81 (coronary), p=<0.001). Transpulmonary thermodilution cardiac output correlated with continuous right-sided thermodilution after valvular (r=0.64, P<0.001) and coronary artery surgery (r=0.81, P<0.001).

synapsesocial.com/papers/6a81bc4328bb6950eb60fe42https://doi.org/10.1510/icvts.2009.204545
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