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October 1, 1979AJP Heart and Circulatory Physiology65 citations

Influence of anesthesia on the response to carotid hypotension in dogs

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RCR. H. CoxRBRoger J. Bagshaw

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Abstract

hemodynamic response to carotid sinus hypotension (CSH) was obtained by bilateral common carotid or brachiocephalic artery occlusion in trained, chronically instrumented dogs lightly pre-medicated with morphine and atropine. Responses were ob-tained before and after anesthesia of equivalent dose by pen-tobarbital (PB, 30 min post), chloralose (C, 30 min post), or halothane (H, 120 min post). Following induction, the animals were intubated and mechanically ventilated by positive pres-sure with 30 % 02 in Nz. In the steady state, mean arterial pressure was unchanged with C and PB but decreased with H (-22-+ 5%). Cardiac output was decreased by all three anes-

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Cox et al. (1979) studied this question.

synapsesocial.com/papers/6a82a2c3aa66c98ddba0c59chttps://doi.org/10.1152/ajpheart.1979.237.4.h424
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