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January 14, 2025Advanced Intelligent Systems26 citationsOpen Access

Artificial Intelligence‐Enhanced, Closed‐Loop Wearable Systems Toward Next‐Generation Diabetes Management

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WHWei HuangJBJing BaiBCBin‐Bin Cui

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Intervention
Artificial intelligence-enhanced closed-loop wearable systems (continuous glucose monitoring systems integrated with insulin delivery)

This review highlights emerging trends in optimizing AI algorithms to enhance the safety and security of closed-loop insulin delivery systems for diabetes management.

Abstract

Recent advancements in wearable healthcare have led to commercially accessible continuous glucose monitoring systems (CGMs) for diabetes management. However, CGMs only monitor glucose levels and lack therapeutic functions, prompting the development of closed‐loop systems that use monitored glucose levels to guide insulin dosing. While promising, these devices also pose risks, such as insulin overdosing, which can cause hypoglycemia. This review summarizes recent advances in integrating artificial intelligence methods with conventional CGMs. The developments in wearable CGMs and progress in insulin delivery technologies are explored, and existing algorithms for glucose prediction in closed‐loop systems are reviewed. Additionally, emerging trends in optimizing these algorithms to enhance the safety and security of closed‐loop insulin delivery systems are highlighted.

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Huang et al. (2025) studied this question.

synapsesocial.com/papers/6a836bc3ec11ec487997e13dhttps://doi.org/10.1002/aisy.202400822
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An AI‐embedded, Wearable Dual Closed‐Loop Insulin Delivery System for Precision Diabetes Management2026 · 11 citations
  2. 2From Finger Pricks to Hybrid Closed‐Loop Artificial Pancreas System: Progress and Future Trends in Continuous Glucose Monitoring Biosensors for Diabetes Care2026
  3. 3Leveraging Artificial Intelligence and Wearable Technologies in Glucose Managenment: A Comprehensive Scoping Review of Current Trends and Future Directions2025 · 2 citations
  4. 4SMART BIOSENSING: AI IN CONTINUOUS GLUCOSE MONITORING2026
  5. 5Technological Advances of Wearable Device for Continuous Monitoring of <i>In Vivo</i> Glucose2024 · 73 citations