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April 30, 2012PLoS ONE137 citationsOpen Access

Hypertension in Women of Reproductive Age in the United States: NHANES 1999-2008

BBBrian T. BatemanKSKate M. ShawEKElena V. Kuklina

Structured PICO

P
Population
5,521 women age 20-44 years old from the United States (NHANES 1999-2008)
O
Outcome
Prevalence of hypertension (determined using blood pressure measurements and/or self-reported medication use)

Hypertension affects approximately 8% of US women of reproductive age, with obesity being a major, modifiable risk factor associated with a greater than 4-fold increased risk.

Abstract

OBJECTIVE: To examine the epidemiology of hypertension in women of reproductive age. METHODS: Using NHANES from 1999-2008, we identified 5,521 women age 20-44 years old. Hypertension status was determined using blood pressure measurements and/or self-reported medication use. RESULTS: The estimated prevalence of hypertension in women of reproductive age was 7.7% (95% confidence interval (CI): 6.9%-8.5%). The prevalence of anti-hypertensive pharmacologic therapy was 4.2% (95% CI 3.5%-4.9%). The prevalence of hypertension was relatively stable across the study period; the age and race adjusted odds of hypertension in 2007-2008 did not differ significantly from 1999-2000 (odds ratio 1.2, CI 0.8 to 1.7, p = 0.45). Significant independent risk factors associated with hypertension included older age, non-Hispanic black race (compared to non-Hispanic whites), diabetes mellitus, chronic kidney disease, and higher body mass index. The most commonly used antihypertensive medications included diuretics, angiotensin-converting enzyme inhibitors (ACE), and beta blockers. CONCLUSION: Hypertension occurs in about 8% of women of reproductive age. There are remarkable differences in the prevalence of hypertension between racial/ethnic groups. Obesity is a risk factor of particular importance in this population because it affects over 30% of young women in the U.S., is associated with more than 4 fold increased risk of hypertension, and is potentially modifiable.

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Cite This Study

Bateman et al. (2012) studied this question.

synapsesocial.com/papers/6a83dbf9b0b8dfdc4c62dc03https://doi.org/10.1371/journal.pone.0036171
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