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May 17, 2013Advanced Synthesis & Catalysis65 citations

An Efficient Route to 3‐Amidylindoles via a Palladium‐ Catalyzed Tandem Reaction of 2‐Alkynylanilines with Isocyanides

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GQGuanyinsheng QiuCCChen ChenLYLiangqing Yao

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Abstract

Abstract A palladium‐catalyzed reaction of 2‐alkynylaniline, isocyanides, and silver acetate is described, leading to 3‐amidylindoles in moderate to good yields. During the process, five new bonds are formed with high reaction efficiency in one‐pot procedure.

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Qiu et al. (2013) studied this question.

synapsesocial.com/papers/6a83e097a0245b7cafe65ce2https://doi.org/10.1002/adsc.201300198
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