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October 5, 2004Angewandte Chemie International Edition192 citations

A DNA Nanomachine Based on a Duplex–Triplex Transition

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YCYi ChenSLSeung‐Hyun LeeCMChengde Mao

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Abstract

Making DNA work: A DNA nanomachine with a mechanism based on a DNA duplex–triplex transition (see figure) was constructed. The key component is a DNA triplex that contains C+GC triplets and is only stable under acidic conditions. The DNA machine uses H+ and OH− ions as fuel and its only waste products are H2O and NaCl.

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Cite This Study

Chen et al. (2004) studied this question.

synapsesocial.com/papers/6a83f4aa53408ed95e4d9045https://doi.org/10.1002/anie.200460789
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