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March 6, 1964Science131 citations

Virus-Specific Double-Stranded RNA in Poliovirus-Infected Cells

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DBDavid BaltimoreYBYechiel BeckerJDJames Darnell

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Abstract

Poliovirus-infected HeLa cells contain a small amount of an RNA that sediments slightly faster than 16S. This RNA is less dense than viral RNA and resists digestion by ribonuclease. It is therefore, considered to be a double-stranded form of poliovirus RNA. A significant amount of this material is found in association with a membranous virus-specific particulate.

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Cite This Study

Baltimore et al. (1964) studied this question.

synapsesocial.com/papers/6a846bb4d7bfb55d35731120https://doi.org/10.1126/science.143.3610.1034
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