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August 19, 20260 citationsOpen Access

Lightweight MobileNet-Based Retinal Disease Classification Using OCT Images

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BSBalwinder SinghDKDr. Navneet KaurSCSikander Singh Cheema

Key Points

  • To develop a lightweight, deep learning-based automated system for the accurate and efficient multi-class classification of common retinal pathologies from optical coherence tomography (OCT) images.
  • Designed a Convolutional Neural Network (CNN) framework utilizing a lightweight MobileNet architecture for retinal image analysis.
  • Trained and validated the model on a public dataset of cross-sectional OCT images across four distinct categories: Normal, Choroidal Neovascularization (CNV), Diabetic Macular Edema (DME), and Drusen.
  • The deep learning model successfully distinguished between healthy scans and three major sight-threatening retinal conditions without requiring manual feature extraction.
  • The automated framework demonstrated computational efficiency suitable for integration into clinical decision-support systems and large-scale retinal screening workflows.

Abstract

Retinal diseases, such as Diabetic Macular Edema (DME), Choroidal Neovascularization (CNV), and drusen, are the leading causes of irreversible vision loss worldwide. Early and accurate diagnosis is critical for effective treatment and preservation of vision. Optical Coherence Tomography (OCT) has emerged as a standard, noninvasive imaging modality that provides high-resolution, cross-sectional images of the retina, en-abling detailed morphological assessment. However, the manual interpretation of a large volume of OCT scans is time-consuming, subjective, and requires significant expertise, leading to poten-tial diagnostic delays and inter-observer variability. This study presents an automated diagnostic system using deep learning to classify retinal OCT images. We propose a Convolutional Neural Network (CNN)-based model designed to accurately and efficiently detect the presence of common retinal pathologies. The model was trained and validated on a publicly available dataset of retinal OCT images categorized into four classes: Normal, CNV, DME, and Drusen. This automated system has the potential to serve as a powerful decision support tool, streamline the diag-nostic workflow, facilitate large-scale screening programs, and ultimately improve patient outcomes through timely intervention.

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Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/6a85632803308d306e2d617dhttps://doi.org/10.5281/zenodo.21967612
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