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December 1, 2007Current Opinion in Anaesthesiology6 citations

Should my outpatient center have a β-blocker protocol?

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LFLee A. Fleisher

Structured PICO

Does perioperative beta-blocker therapy reduce perioperative cardiac events in patients undergoing ambulatory surgery?

P
Population
Patients undergoing ambulatory or noncardiac surgery
I
Intervention
Perioperative beta-blocker therapy
O
Outcome
Perioperative cardiac eventshard clinical

Perioperative beta-blockade should be continued in patients already on therapy during ambulatory surgery, but prophylactic initiation is not recommended for those without indications.

Abstract

PURPOSE OF REVIEW: Perioperative beta-blockade has been advocated by multiple authors and recent guidelines as a strategy to reduce cardiac risk in noncardiac surgery. Knowledge about application of this treatment modality to the ambulatory surgery population is poor. RECENT FINDINGS: Although the initial trial in patients with a positive stress test undergoing major vascular surgery demonstrated significantly fewer perioperative cardiac events among those randomized to perioperative beta-blocker therapy, more recent studies in patients without documented coronary artery disease undergoing major noncardiac surgical procedures were unable to demonstrate efficacy. Guidelines from the American Heart Association/American College of Cardiology have been reported and advocated class I recommendations for perioperative beta-blockade only for patients previously taking beta-blockers and those patients with a positive stress test undergoing vascular surgery. There was insufficient evidence to make a recommendation in low-risk surgery. SUMMARY: Based upon the available evidence and guidelines, patients currently taking beta-blockers and undergoing ambulatory surgery should continue these agents and protocols employing this strategy should be beneficial. In patients who are not currently taking beta-blockers and in whom long-term therapy is not warranted, current evidence does not support instituting prophylactic therapy in the ambulatory surgery population.

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Lee A. Fleisher (2007) studied this question.

synapsesocial.com/papers/6a865ea1bf47e2fe102fd410https://doi.org/10.1097/aco.0b013e3282f19339
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Perioperative β-Blockers in Patients Undergoing Noncardiac Surgery-Scientific Misconduct and Clinical Guidelines2017 · 7 citations
  2. 2β-Blockers and Reduction of Cardiac Events in Noncardiac Surgery2002 · 123 citations
  3. 3β-Blockers and Reduction of Cardiac Events in Noncardiac Surgery2002 · 334 citations
  4. 4Pro: Beta-Blockers Are Indicated for Patients at Risk for Cardiac Complications Undergoing Noncardiac Surgery2006 · 34 citations
  5. 5Perioperative beta-blockers in noncardiac surgery: The evidence continues to evolve2014 · 6 citations