Operative treatment resulted in similar rates of good radiological outcomes compared to conservative treatment in children with severe Perthes' disease (62.7% vs 71.9%; p > 0.05).
Cohort (n=166)
Does operative treatment improve radiological outcomes compared to conservative treatment in children under six with severe Perthes' disease?
In children under six with severe Perthes' disease, operative treatment does not significantly improve radiological outcomes compared to conservative management.
Absolute Event Rate: 62.7% vs 71.9%
p-value: p=> 0.05
Children presenting with Perthes' disease before their sixth birthday are considered to have a good prognosis. We describe 166 hips in children in this age group. The mean age at onset of the disease was 44 months (22 to 72). Mild forms (Catterall I and II) were treated conservatively and severe forms (Catterall III and IV) either conservatively or operatively. The aim of the former treatment was to restrict weight-bearing. Operative treatment consisted of innominate osteotomy and was indicated by a Conway type-B appearance on the bone scan. All the patients were followed to skeletal maturity with a mean follow-up of 11 years (8 to 15). The end results were evaluated radiologically using the classifications of Stulberg and Mose. A total of 50 hips were Catterall grade-I or grade-II, 65 Catterall grade-III and 51 Catterall grade-IV. All hips with mild disease had a good result at skeletal maturity. Of the hips with severe disease 78 (67.3%) had good (Stulberg I and II), 26 (22.4%) fair (Stulberg III) and 12 (10.3%) poor results (Stulberg IV and V). Of the Catterall grade-III hips 38 were treated conservatively of which 31 (81.6%) had a good result, six (15.8%) a fair and one (2.6%) a poor result. Operative treatment was carried out on 27 Catterall grade-III hips, of which 21 (77.8%) had a good, four (14.8%) a fair and two (7.4%) a poor result. By comparison conservative treatment of 19 Catterall grade-IV hips led to ten (52.7%) good, seven (36.8%) fair and two (10.5%) poor results. Operative treatment was carried out on 32 Catterall grade-IV hips, of which 16 (50.0%) had a good, nine (28.1%) a fair and seven (21.9%) a poor result. We confirm that the prognosis in Perthes' disease is generally good when the age at onset is less than six years. In severe disease there is no significant difference in outcome after conservative or operative treatment (p > 0.05). Catterall grade-III hips had a better outcome according to the Stulberg and Mose criteria than Catterall grade-IV hips, regardless of the method of treatment.
Canavese et al. (2008) conducted a cohort in Perthes' disease (n=166). Operative treatment (innominate osteotomy) vs. Conservative treatment (restricted weight-bearing) was evaluated on Good radiological result (Stulberg I and II) at skeletal maturity in severe disease (p=> 0.05). Operative treatment resulted in similar rates of good radiological outcomes compared to conservative treatment in children with severe Perthes' disease (62.7% vs 71.9%; p > 0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: