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This book contains a comprehensive and critical review of methods for the determination of uric acid in blood serum and in urine. The author reports new methods of his own as well as suggestions for careful control of conditions in methods previously reported. A large series of analyses gives comparative results of the commonly used methods and of his methods. Studies of serum and the uric acid content of the urine for normal persons were performed, the results of which are reported in detail. Uric acid clearance studies, total daily excretion of uric acid and the effect of diet and of diuresis are all studied in detail. The mechanism of uric acid excretion is considered. All persons used for study were free from any disturbance of uric acid metabolism. The bibliography of nearly 400 references indicates the comprehensive nature of this book, which should be a useful work of reference
A 1938 study studied this question.