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The carbon monoxide (CO)-carrying palladium nanosheet (PdNS-CO) was exploited as a photothermally triggered donor of CO. Irradiating material containing PdNS-CO with 808 nm-wavelength light caused a rapid heating of the material, triggering a release of CO. The enhanced permeability and retention (EPR) effect was found to be improved by such released CO and resulted in an increase in the accumulation of PdNS-CO at tumors and hence promoted its use in photothermal therapy (PTT) using a low laser power density.
Wang et al. (2018) studied this question.