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May 1, 1978Anesthesiology130 citationsOpen Access

Comparative Penetration of Glycopyrrolate and Atropine across the Blood—Brain and Placental Barriers in Anesthetized Dogs

APAnthony G. ProakisGHGladys B. Harris

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Abstract

The levels of 14C-glycopyrroIate, a quaternary ammonium anticholinergic agent, appearing in cerebrospinal fluid (CSF) and serum (S) following a single intravenous dose of 0.1 mg/kg were determined in mongrel dogs during barbiturate anesthesia and compared with levels reached in dogs treated with sim

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Proakis et al. (1978) studied this question.

synapsesocial.com/papers/6a8a53f77f5a142c17c141c1https://doi.org/10.1097/00000542-197805000-00007
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