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August 23, 1968Science112 citations

Interferon: Protection of Cells Infected with an Intracellular Protozoan ( Toxoplasma gondii )

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JRJack S. RemingtonTMThomas C. Merigan

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Abstract

Chick and mouse cell monolayers treated with interferon were significantly protected from destruction by toxoplasma. The results suggest that fewer numbers of organisms were released from interferon-treated cells. Interferons were uniformly more active in a viral assay than in a toxoplasma assay, and they had the same properties in both assays. The data suggest that interferon activity may be directed against organisms phylogenetically higher than viruses.

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Cite This Study

Remington et al. (1968) studied this question.

synapsesocial.com/papers/6a8d234db4e2d843785be54fhttps://doi.org/10.1126/science.161.3843.804
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