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July 11, 2019Anesthesia & Analgesia16 citations

Factors Associated With Failure of Spinal Anesthetic: An 8-Year Retrospective Analysis of Patients Undergoing Elective Hip and Knee Joint Arthroplasty

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JCJane ColishAMAndrew D. MilnePBPaul Brousseau

Key Result

Spinal anesthetic failure occurred in 3.8% of cases, with higher odds for hip vs knee arthroplasty (OR 1.90), L5-S1 vs L2-3 insertion (OR 7.66), and 22-gauge vs 25-gauge needles (OR 2.17).

Study Design

Type

Observational (n=3,542)

Structured PICO

What factors are associated with the failure of spinal anesthetic in patients undergoing elective hip and knee joint arthroplasty?

P
Population
3,542 spinal anesthetics administered for elective hip and knee joint arthroplasty over an 8-year period.
E
Exposure
Spinal anesthetic
O
Outcome
Failure of spinal anesthetic

Failure of spinal anesthesia in joint arthroplasty is associated with specific patient and procedural factors, including younger age, lower BMI, hip surgery, lower lumbar insertion, larger needle size, and hyperbaric bupivacaine.

Main Result

Odds Ratio: 1.9 (95% CI 1.28–2.84)

Abstract

The primary outcome of this 8-year retrospective review was the failure of spinal anesthetic (SA) in elective hip and knee joint arthroplasty surgery. Of 3542 SAs, a total of 135 failures were identified (3.8%). Factors associated with increased odds of failure were younger age (odds ratio OR, 1.03; 95% confidence interval CI, 1.01-1.05), lower body mass index (BMI; OR, 1.04 1.01-1.08), hip arthroplasty (OR, 1.90 1.28-2.84) compared to knee arthroplasty, needle insertion at L4-5 (OR, 4.61 2.02-10.54) and L5-S1 (OR, 7.66 2.47-23.7) compared to L2-3, 22-gauge needle size (OR, 2.17 1.34-3.52) compared to 25-gauge needle, and hyperbaric bupivacaine (OR, 1.66 1.09-2.53) compared to isobaric bupivacaine.

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Cite This Study

Colish et al. (2019) conducted an observational in Elective hip and knee joint arthroplasty (n=3,542). Hip arthroplasty (and other patient/procedural factors) vs. Knee arthroplasty was evaluated on Failure of spinal anesthetic (SA) (OR 1.90, 95% CI 1.28-2.84). Spinal anesthetic failure occurred in 3.8% of cases, with higher odds for hip vs knee arthroplasty (OR 1.90), L5-S1 vs L2-3 insertion (OR 7.66), and 22-gauge vs 25-gauge needles (OR 2.17).

synapsesocial.com/papers/6a903e797b6e700e2c8a47a0https://doi.org/10.1213/ane.0000000000004304
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