PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
August 28, 2018Emerging infectious diseases79 citationsOpen Access

Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010–2016

YLYu LiPWPeng WuQLQiaohong Liao

Key Result

Coxsackievirus A6 emerged as a predominant causative agent of hand, foot and mouth disease in China, accounting for 25.9% of mild and 15.2% of severe cases in 2013, and 25.8% of mild and 16.9% of severe cases in 2015.

Study Design

Type

Observational (n=693,580)

Multicenter

Yes

Structured PICO

P
Population
693,580 individual illness episodes of hand, foot and mouth disease reported across 23 provinces in China between 2010 and 2016.
O
Outcome
Proportion of mild and severe cases caused by Coxsackievirus A6

Coxsackievirus A6 emerged as a predominant causative agent of hand, foot and mouth disease in China in 2013 and 2015.

Limitations

  • Serotyping results of other enteroviruses tend to reflect areas with more intensive HFMD transmission because local CDCs generally select areas where the most cases are detected for further serotyping.
  • Not all cases have etiologic results, and testing methods vary among hospitals.
  • Further serotyping on other enteroviruses is not conducted as a routine practice.

Abstract

Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015. This virus strain accounted for 25.9% of mild and 15.2% of severe cases in 2013 and 25.8% of mild and 16.9% of severe cases in 2015.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Li et al. (2018) conducted an observational in Hand, foot and mouth disease (HFMD) (n=693,580). Enterovirus serotypes (including CV-A6, EV-A71, CV-A16) was evaluated on Proportion of HFMD cases caused by specific enterovirus serotypes. Coxsackievirus A6 emerged as a predominant causative agent of hand, foot and mouth disease in China, accounting for 25.9% of mild and 15.2% of severe cases in 2013, and 25.8% of mild and 16.9% of severe cases in 2015.

synapsesocial.com/papers/6a93965a4e47fb946fafcce6https://doi.org/10.3201/eid2410.171953
Ask AI
Helpful
Bookmark
Share
View Full Paper