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February 7, 2012The Korean Journal of Thoracic and Cardiovascular Surgery6 citationsOpen Access

Surgical Experience of Ascending Aorta and Aortic Valve Replacement in Patient with Calcified Aorta

SCSuryeun ChungPPPyo Won ParkMCMin Suk Choi

Key Result

Ascending aorta and aortic valve replacement under hypothermic circulatory arrest in patients with a calcified aorta resulted in no hospital mortality and no new onset of cerebral infarction.

Study Design

Type

Observational (n=11)

Multicenter

No

Structured PICO

P
Population
11 patients (mean age 68 years, 54.5% female) with calcified ascending aorta who underwent ascending aorta and aortic valve replacement under hypothermic circulatory arrest, followed for a mean of 32 months.
I
Intervention
Ascending aorta and aortic valve replacement under hypothermic circulatory arrest
O
Outcome
Postoperative mortality and morbidity (including cerebral infarct and cardiovascular accident)hard clinical

Ascending aorta and aortic valve replacement under hypothermic circulatory arrest is a safe technique that avoids cerebrovascular complications in patients with a calcified aorta.

Limitations

  • Small sample size of only 11 patients
  • Retrospective, single-center study design
  • Lack of a control group for direct comparison

Abstract

BACKGROUND: The conventional method of aortic cross-clamping is very difficult and increases the risk of cerebral infarct due to embolism of the calcified aorta in these patients. Accordingly, we analyzed our experience with 11 cases of ascending aorta and aortic valve replacement with hypothermic circulatory arrest. MATERIALS AND METHODS: From January 2002 to December 2009, 11 patients had ascending aorta and aortic valve replacement with hypothermic arrest at our hospital. We performed a retrospective study. RESULTS: There were 5 males and 6 females, with a mean age of 68 years (range, 44 to 82 years). Eight patients had aortic stenosis, and 3 patients had aortic regurgitation. An aortic cannula was inserted into the right axillary artery in 3 patients and ascending aorta in 6 patients. Two patients with aortic regurgitation had a remote access perfusion catheter inserted though the right femoral artery. The mean cardiopulmonary bypass time was 180 minutes (range, 110 to 306 minutes) and mean hypothermic circulatory arrest time was 30 minutes (range, 20 to 48 minutes). The mean rectal temperature during hypothermic circulatory arrest was 21℃ (range, 19℃ to 23℃). No patient had any new onset of cerebral infarct or cardiovascular accident after surgery. There was no hospital mortality. Early complications occurred in 1 patient who needed reoperation due to postoperative bleeding. Late complications occurred in 1 patient who underwent a Bentall operation due to prosthetic valve endocarditis. The mean follow-up duration was 32 months (range, 1 month to 8 years) and 1 patient died suddenly due to unknown causes after 5 years. CONCLUSION: Patients with a calcified aorta can be safely treated with a technique based on aorta and aortic valve replacement under hypothermic circulatory arrest.

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Cite This Study

Chung et al. (2012) conducted an observational in Calcified ascending aorta requiring aortic valve replacement (n=11). Ascending aorta and aortic valve replacement under hypothermic circulatory arrest was evaluated on Hospital mortality and new onset of cerebral infarct or cardiovascular accident. Ascending aorta and aortic valve replacement under hypothermic circulatory arrest in patients with a calcified aorta resulted in no hospital mortality and no new onset of cerebral infarction.

synapsesocial.com/papers/6a93f1cebeaf7a0a159c45ffhttps://doi.org/10.5090/kjtcs.2012.45.1.24
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