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April 28, 1966New England Journal of Medicine27 citations

IV. Septic Shock–Pathogenesis and Treatment

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LWLouis WeinsteinAKAlbert S. Klainer

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Abstract

SEPTIC shock is a dynamic syndrome induced by infections of varying type in which inadequate perfusion of tissues with blood develops. Although the microcirculation of the capillary loop is the final determinant of the events that occur in this condition, multiple factors are involved in the genesis and persistence of progressive decompensation of the capillary circulation and the cells that it supports. Effective therapy of septic shock requires knowledge of its pathogenesis, anticipation and recognition of the clinical picture, the use of available bedside and laboratory technics for assessing the nature and degree of the derangements and rapid initiation of . . .

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Weinstein et al. (1966) studied this question.

synapsesocial.com/papers/6a94766b5cc4cfd2f72de0achttps://doi.org/10.1056/nejm196604282741708
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