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February 1, 2000Annual Review of Medicine249 citations

Bacterial Vaginosis

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JSJack D. Sobel

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Abstract

Bacterial vaginosis represents a unique upheaval of the complex vaginal bacterial flora with disappearance of lactobacilli and overgrowth of Gardnerella vaginalis and resident anaerobic vaginal bacteria. Little progress has occurred in identifying causal factors, although the pathophysiology of this syndrome is better understood. Although symptoms are easily recognizable, obstetric and gynecologic complications continue to increase in number. Bacterial vaginosis is far more than a nuisance infection. Problems with diagnosis continue to dominate clinical practice, although new tests have been introduced. Therapeutic options have increased, although recurrent disease remains common, and management of this common complication constitutes a major challenge.

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Jack D. Sobel (2000) studied this question.

synapsesocial.com/papers/6a951206397e3dbeede61dd6https://doi.org/10.1146/annurev.med.51.1.349
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The treatment of bacterial vaginosis with a 3 day course of 2% clindamycin cream: results of a multicentre, double blind, placebo controlled trial. B V Investigators Group.1995 · 20 citations
  2. 2A randomised comparison of strategies for reducing infective complications of induced abortion1998 · 91 citations
  3. 3Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations1983 · 326 citations
  4. 4Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: A placebo-controlled, double-blind study1994 · 349 citations
  5. 5Plasma cell endometritis in women with symptomatic bacterial vaginosis1995 · 195 citations