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June 11, 2010Applied and Environmental Microbiology90 citationsOpen Access

Novel Florfenicol and Chloramphenicol Resistance Gene Discovered in Alaskan Soil by Using Functional Metagenomics

KLKevin S. LangJAJanet AndersonŠSŠtefan Schwarz

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Abstract

Functional metagenomics was used to search for florfenicol resistance genes in libraries of cloned DNA isolated from Alaskan soil. A gene that mediated reduced susceptibility to florfenicol was identified and designated pexA. The predicted PexA protein showed a structure similar to that of efflux pumps of the major facilitator superfamily.

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Lang et al. (2010) studied this question.

synapsesocial.com/papers/6a952d6ba9fda6dc960f44abhttps://doi.org/10.1128/aem.00323-10
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