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April 1, 2018Journal of Visualized Surgery8 citationsOpen Access

Intimal re-layering technique for type A acute aortic dissection—reconstructing the intimal layer continuity to induce remodeling of the false channel

ENEugénio NeriETEnrico TucciGTGiulio Tommasino

Key Result

The intimal re-layering technique for type A acute aortic dissection resulted in no intraoperative deaths or neurologic deficits in 11 patients, and obliterated the proximal false channel in 10 cases.

Study Design

Type

Observational (n=11)

Structured PICO

P
Population
11 patients (median age 74 years, 36.4% female) undergoing emergency surgery for type A acute aortic dissection using a novel intimal re-layering technique, followed for a median of 443 days.
E
Exposure
Intimal re-layering technique during emergency surgery (reinforcing intimal layer at arch level, eliminating inter-luminal communications using suture lines around arch vessels, providing elephant trunk configuration) using systemic circulatory arrest under moderate hypothermia (26 °C) and selective cerebral perfusion.
O
Outcome
Safety (mortality, neurologic deficit) and aortic remodeling (false channel obliteration) assessed by CT scan at 3 months and 1 year.safety

The intimal re-layering technique for type A acute aortic dissection appears safe and effective in inducing aortic remodeling and obliterating the false channel in an initial case series.

Abstract

BACKGROUND: Residual false channel is common after repair of type A acute aortic dissection (TAAAD). Starting from our recent series of TAAAD patients we carried out a retrospective analysis, regarding the failure of primary exclusion at the time of the initial operation. We classified the location of the principal entry tears perfusing the residual false channel. The proposed technique represents our attempt to correct the mechanism of false channel perfusion during primary repair. We describe a new technique designed to address some limitations of standard hemiarch aortic replacement. Its goal are: (I) to reinforce the intimal layer at the arch level; (II) to eliminate inter-luminal communications at the arch level using suture lines around the arch vessels; (III) to provide an elephant trunk configuration for further interventions. METHODS: Between August 2016 and January 2018, 11 patients underwent emergency surgery using this technique; 7 were men; the median age was 74 years. All patients were treated using systemic circulatory arrest under moderate hypothermia (26 °C) and selective cerebral perfusion. All patients had supra-coronary repair; 1 patient had aortic valve replacement + CABG. In the first two patients a manual suture around supra-aortic trunks was used; the subsequent seven patients were treated with a mechanical suture bladeless device. CT scan follow up was performed in all survivors with controls before discharge 3 months and 1 year after operation. RESULTS: No patient died in the operating room and no neurologic deficit was observed in this initial experience. One patient died in POD 5th for low cardiac output syndrome. Median ICU stay was 3 days (IQR, 2-6 days). Hospital mean length of stay was 15.2±8 days. Median cardiopulmonary bypass time was 130 min (IQR, 110-141 min); median arrest time for re-layering was 17 min (IQR, 16-20 min); median total arrest was 36 min (IQR, 29-39 min). Distal aortic anastomosis was performed in zone 0 in 4 patients, zone 1, with innominate replacement, in 5 patients, in zone 2, with branches to innominate and left common carotid arteries, in 2 patients. Median follow up (closing date 06/01/2018) was 443 days (IQR, 262-557 days); no late deaths occurred. No dehiscence at the level of stapler or manual sutures was observed. Proximal 1/3 of the thoracic aorta false channel was obliterated in all cases but one; in 3 cases complete exclusion of the false channel was obtained after operation. In one case stent graft completion was required. CONCLUSIONS: This technique combines the advantages of arch replacement to the simplicity of anterior hemiarch repair. This study demonstrates the safety of the procedure and the possibility to induce aortic remodeling without complex arch replacement.

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Cite This Study

Neri et al. (2018) conducted an observational in Type A acute aortic dissection (n=11). Intimal re-layering technique was evaluated. The intimal re-layering technique for type A acute aortic dissection resulted in no intraoperative deaths or neurologic deficits in 11 patients, and obliterated the proximal false channel in 10 cases.

synapsesocial.com/papers/6a97b321d72f642c28a665d5https://doi.org/10.21037/jovs.2018.04.09
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