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April 1, 1960Circulation43 citations

Surgical Relief of Aortic Insufficiency by Direct Operation on the Aortic Valve

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WMWilliam H. MullerWWW. Dean WarrenJDJohn F. Dammann

Key Result

Direct surgical operations on the aortic valve in 19 patients with aortic insufficiency resulted in 11 patients (57.9%) being well or markedly improved, while 8 (42.1%) died.

Study Design

Type

Observational (n=19)

Multicenter

No

PICO

P
Population
19 patients with aortic insufficiency and heart failure who underwent direct surgical operations on the aortic valve.
E
Exposure / Comparator
Direct operation on the aortic valve
O
Primary Outcome
Clinical improvement (well or markedly improved)

Abstract

The natural history of patients with aortic insufficiency and the previous experimental and clinical operations devised for its relief are reviewed. Methods that have been used at the University of Virginia Hospital for treatment of aortic insufficiency are reported. These procedures include the release of the fixed valve leaflet and removal of calcium from it, aortic valve leaflet extension with suture of a small piece of compressed polyvinyl sponge or Teflon fabric to the edge of one of the leaflets, excision and replacement of a portion of the valve with a synthetic leaflet, and complete subcoronary replacement of the valve with a prosthesis. To relieve isolated rheumatic aortic insufficiency, an annulus has been constricted or a bicuspid aortic valve has been created. Insufficiency resulting from perforation of one or more valve leaflets by subacute bacterial endocarditis has been treated by closure of the perforations. Nineteen patients underwent 21 operations for the correction of aortic insufficiency. All had been in, or were in, heart failure, and several had significant coronary artery disease or multivalvular disease. Eleven of the 19 patients are well or markedly improved. Eight died during or after the operative procedure. It is concluded that a direct attack upon the insufficient aortic valve is the procedure of choice at the present time.

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Cite This Study

Muller et al. (1960) conducted an observational in Aortic insufficiency (n=19). Direct operation on the aortic valve was evaluated on Clinical improvement (well or markedly improved). Direct surgical operations on the aortic valve in 19 patients with aortic insufficiency resulted in 11 patients (57.9%) being well or markedly improved, while 8 (42.1%) died.

synapsesocial.com/papers/6a9aa1be262e4da96990b8dchttps://doi.org/10.1161/01.cir.21.4.587
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Valve repair for aortic insufficiency: surgical classification and techniques1997 · 112 citations
  2. 2The Direct Approach for the Correction of Aortic Insufficiency1961 · 37 citations
  3. 3Aortic valve-sparing operations in patients with ascending aortic aneurysms1997 · 17 citations
  4. 4Valve-sparing operations on the aortic valve and the ascending aorta: radical correction of congenital and acquired heart diseases. Immediate outcomes2021 · 2 citations
  5. 5Aortic valve leaflet sparing and salvage surgery: evolution of techniques for aortic root reconstruction2003 · 80 citations