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April 16, 2008Anesthesia & Analgesia159 citations

Intravenous Lipid Infusion in the Successful Resuscitation of Local Anesthetic-Induced Cardiovascular Collapse After Supraclavicular Brachial Plexus Block

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JWJulio A. WarrenRTR. ThomaAGAlexandru Valentin Georgescu

Key Result

Intravenous lipid infusion successfully restored cardiovascular activity and hemodynamic stability after 10 minutes of unsuccessful resuscitation for local anesthetic-induced cardiovascular collapse.

Study Design

Type

Case Report (n=1)

Structured PICO

Does intravenous lipid infusion improve cardiovascular activity and hemodynamic stability in a patient with local anesthetic-induced cardiovascular collapse?

P
Population
A single case of local anesthetic-induced cardiovascular collapse after supraclavicular brachial plexus block.
I
Intervention
Intravenous lipid infusion (intralipid)
O
Outcome
Restoration of cardiovascular activity and hemodynamic stabilitysafety

This case demonstrates the utility of intravenous lipid rescue for local anesthetic-induced cardiovascular toxicity during prolonged resuscitative efforts.

Abstract

In Brief We describe a case of successful resuscitation with an IV lipid infusion of local anesthetic-induced cardiovascular toxicity after supraclavicular brachial plexus block with mepivacaine and bupivacaine. Lipid therapy was initiated after 10 min of unsuccessful resuscitation and resulted in restoration of cardiovascular activity and hemodynamic stability. This case illustrates the utility of IV lipid therapy in the treatment of local anesthetic toxicity. IMPLICATIONS: We report a case of successful resuscitation with intralipid infusion after cardiovascular collapse after supraclavicular block with ropivacaine and mepivacaine. This case demonstrates the utility of lipid rescue for presumed local anesthetic toxicity during prolonged resuscitative efforts.

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Cite This Study

Warren et al. (2008) conducted a case report in Local anesthetic-induced cardiovascular toxicity (n=1). Intravenous lipid infusion was evaluated on Restoration of cardiovascular activity and hemodynamic stability. Intravenous lipid infusion successfully restored cardiovascular activity and hemodynamic stability after 10 minutes of unsuccessful resuscitation for local anesthetic-induced cardiovascular collapse.

synapsesocial.com/papers/6a9cd3f9a09733fe8776e91dhttps://doi.org/10.1213/01.ane.0000281434.80883.88
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