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November 19, 2015The Anatolian Journal of Cardiology33 citationsOpen Access

SYNTAX score predicts postoperative atrial fibrillation in patients undergoing on-pump isolated coronary artery bypass grafting surgery

ÇGÇetin GeçmenGGGamze Babür GülerEEEmrah Erdoğan

Key Result

A higher preoperative SYNTAX score was independently associated with an increased risk of postoperative atrial fibrillation (OR 1.139) in patients undergoing isolated on-pump CABG.

Study Design

Type

Observational (n=94)

Multicenter

No

Structured PICO

Does a higher SYNTAX score predict postoperative atrial fibrillation in patients undergoing isolated on-pump CABG?

P
Population
94 adult patients with sinus rhythm undergoing isolated on-pump coronary artery bypass grafting, followed until hospital discharge to assess predictors of postoperative atrial fibrillation.
E
Exposure
Preoperative SYNTAX score assessment
O
Outcome
Postoperative atrial fibrillation (PoAF)hard clinical

A higher preoperative SYNTAX score is an independent predictor of postoperative atrial fibrillation in patients undergoing isolated on-pump CABG.

Main Result

Odds Ratio: 1.139 (95% CI 1.05–1.235)

p-value: p=0.002

Limitations

  • Relatively small sample size
  • Non-randomized nature of the study
  • Left atrial volume was not calculated
  • Long-term clinical course of the patients was not recorded
  • Daily ECGs might have missed some paroxysmal AF episodes
  • Inflammatory markers were not measured
  • CABG operations were not performed by a single operator or surgical team

Abstract

OBJECTIVE: Atrial fibrillation (AF) is the most common arrhythmia following coronary artery by-pass graft surgery (CABG). The value of SYNTAX score to predict postoperative atrial fibrillation (PoAF) has not been clearly addressed. We aimed to evaluate this relationship in patients undergoing isolated CABG. METHODS: This study was designed as a single-center, non-randomized, observational, prospective study. Ninety-four patients undergoing isolated on-pump CABG, who had sinus rhythm and were older than 18 years, were enrolled. Demographic characteristics of the patients were recorded; SYNTAX score was calculated preoperatively for each patient. The univariate and multivariate logistic regression analysis were used to determine for predictors of PoAF. RESULTS: The median SYNTAX score of the enrolled patients was 21, (56-5). PoAF was observed in 31 (33.3%) patients. Univariate logistic regression showed that age, chronic obstructive pulmonary disease (COPD), red blood cell distribution width (RDW), urea, initial troponin I, peak postoperative troponin I, interventricular septum, left atrial diameter, and SYNTAX score were significantly associated with the frequency of PoAF following CABG. An independent association was identified with age ß: 0.088, p:0.023, OR: 1.092, 95% CI (1.012-1.179), COPD (ß: 2.222, p:0.003, OR: 9.228, 95% CI (2.150-39.602), and SYNTAX score (ß: 0.130, p:0.002, OR: 1.139, 95% CI (1.050-1.235). CONCLUSION: This study showed that a higher SYNTAX score was related to more frequent PoAF in patients undergoing isolated on-pump CABG.

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Cite This Study

Geçmen et al. (2015) conducted an observational in Coronary artery disease requiring isolated on-pump CABG (n=94). SYNTAX score vs. Lower SYNTAX score was evaluated on Postoperative atrial fibrillation (PoAF) (OR 1.139, 95% CI 1.050-1.235, p=0.002). A higher preoperative SYNTAX score was independently associated with an increased risk of postoperative atrial fibrillation (OR 1.139) in patients undergoing isolated on-pump CABG.

synapsesocial.com/papers/6a9fb99bc2a6bb3d9844a9abhttps://doi.org/10.5152/anatoljcardiol.2015.6483
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