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December 1, 1997Biochemistry183 citations

X-ray Structure of Motor and Neck Domains from Rat Brain Kinesin,

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Population

Rat brain kinesin (motor and neck domains)

Design

Preclinical

Key result

The X-ray structure of rat kinesin head and neck domains reveals novel features in the N-terminal region and C-terminal transition, suggesting a different mechanism of force transduction than myosin.

Authors

SSStefan SackJMJens MüllerAMAlexander Marx

Discussion

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Overview

The structural determination of rat brain kinesin motor and neck domains reveals differences from myosin, suggesting distinct mechanisms of force transduction.

Structured PICO

P
Population
Rat brain kinesin (motor and neck domains)
I
Intervention
X-ray crystallography
O
Outcome
X-ray structure of rat kinesin head and neck domainssurrogate

The structural determination of rat brain kinesin motor and neck domains reveals differences from myosin, suggesting distinct mechanisms of force transduction.

Cite This Study

Sack et al. (1997) studied this question. The X-ray structure of rat kinesin head and neck domains reveals novel features in the N-terminal region and C-terminal transition, suggesting a different mechanism of force transduction than myosin.

synapsesocial.com/papers/6aa03a3aa8b4be248fe9ebeehttps://doi.org/10.1021/bi9722498
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