Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI

Key Points

• To evaluate the effectiveness of iFR-guided versus FFR-guided strategies in reducing major adverse cardiac events in patients with stable angina or acute coronary syndrome.
• Randomized trial comparing iFR and FFR-guided revascularization strategies.
• Follow-up duration of 12 months.
• ClinicalTrials.gov number NCT02166736.
• iFR-guided revascularization showed a noninferior rate of major adverse cardiac events compared to FFR at 12 months (exact rates not provided).
• Both guidance methods were effective in managing patients with stable angina or acute coronary syndrome.