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March 18, 2017New England Journal of MedicineOpen Access

Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI

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Authors

MGMatthias GötbergInterventional CardiologyEvald Høj ChristiansenEvald Høj ChristiansenInterventional / Structural CardiologyIGIngibjörg Jóna GuðmundsdóttirInterventional / Structural Cardiology

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Implication

Randomized trial compares iFR and FFR guidance for PCI outcomes in patients with angina, suggesting iFR is a viable alternative.

Key Points

  • To evaluate the effectiveness of iFR-guided versus FFR-guided strategies in reducing major adverse cardiac events in patients with stable angina or acute coronary syndrome.
  • Randomized trial comparing iFR and FFR-guided revascularization strategies.
  • Follow-up duration of 12 months.
  • ClinicalTrials.gov number NCT02166736.
  • iFR-guided revascularization showed a noninferior rate of major adverse cardiac events compared to FFR at 12 months (exact rates not provided).
  • Both guidance methods were effective in managing patients with stable angina or acute coronary syndrome.

Cite This Study

Götberg et al. (2017) studied this question.

synapsesocial.com/papers/6970ddc8cfea4c1fcf6a58d4https://doi.org/10.1056/nejmoa1616540
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