August 28, 2012Open Access
Fractional Flow Reserve–Guided PCI versus Medical Therapy in Stable Coronary Disease
Key Result
FFR-guided PCI decreased the need for urgent revascularization compared to medical therapy alone in patients with stable coronary artery disease and significant stenoses.
Structured PICO
Does FFR-guided PCI plus the best available medical therapy reduce the need for urgent revascularization in patients with stable coronary artery disease and functionally significant stenoses?
P
Population
Patients with stable coronary artery disease and functionally significant stenoses
I
Intervention
FFR-guided PCI plus the best available medical therapy
C
Comparator
Best available medical therapy alone
O
Outcome
Need for urgent revascularizationhard clinical
In patients with stable coronary artery disease and functionally significant stenoses, FFR-guided PCI reduces the need for urgent revascularization compared to medical therapy alone.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
In patients with stable coronary artery disease and functionally significant stenoses, FFR-guided PCI plus the best available medical therapy, as compared with the best available medical therapy alone, decreased the need for urgent revascularization. In patients without ischemia, the outcome appeared to be favorable with the best available medical therapy alone. (Funded by St. Jude Medical; ClinicalTrials.gov number, NCT01132495.).
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Authors
Bernard De Bruyne
Università Cattolica del Sacro Cuore
Nico H.J. Pijls
Interventional Cardiology
B
Bindu Kalesan
Boston University
Journals
New England Journal of Medicine
Actions
Institutions
Stanford University
Karolinska Institutet
Radboud University Nijmegen
References and Citations
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