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MRAs reduce CV events similarly in Black and non-Black HF patients; confirms consistent efficacy across races and supports broad use.

Pediatric PH risk model may refine prognostication; leaves open whether it improves outcomes over expert opinion or adult-derived tools.
CRT-D associated with lower mortality than CRT-P in NICM; leaves open whether defibrillator benefit holds in randomized trials.

May inform risk assessment in Korean children with LQTS; extends sparse Asian data but leaves generalizability open.

Genetic testing may aid fetal cardiomyopathy evaluation; leaves open causal links and outcome improvements pending prospective data.

IDA on post-PFO CTA was associated with recurrent stroke; leaves open whether optimization reduces events in trials.

TF-TAVR may be feasible for high-risk PNAR; leaves open randomized confirmation before practice change.

Microelectrodes may enhance gap detection during ablation; hypothesis-generating and should not yet change practice.

PFA may be preferred for paroxysmal AF ablation; confirms and extends prior RCT findings in larger pooled analysis.
Current evidence supports IL-6 as a biomarker of disease activity in HCM and DCM, though its causal pathogenic role and potential as a direct therapeutic target remain unproven.
