Explore
Search the literature, follow the researchers shaping cardiology, and read the debates the field is actually having.
Researchers to follow
See all
Are you a researcher?
Browse the literature
Trending in cardiology
Updated 11:06 PM UTC
Rank
Paper
Published
Coverage
1
Interleukin-6 Inhibition with Ziltivekimab for Atherosclerotic Disease
New England Journal of Medicine· Ridker P et al.
Nov 7
2
Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a)
New England Journal of Medicine· Cho L et al.
Nov 7
3
ANGPTL4 Inhibition in Adults with Elevated Triglyceride Levels
New England Journal of Medicine· O’Donoghue M et al.
Nov 9
4
Discontinuing Statins in Older Adults without Cardiovascular Disease
New England Journal of Medicine· Rodondi N et al.
Nov 7
141 likes6 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan (X)
Podcast: Nov 13, 2026 This Week in Cardiology
5
Community and EMS Interventions to Improve Survival in Cardiac Arrest
New England Journal of Medicine· Hansen C et al.
Nov 8
6
Left Bundle-Branch Pacing versus Right Ventricular Pacing for Atrioventricular Block
New England Journal of Medicine· Qian Z et al.
Nov 8
100 likes6 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan (X)
Podcast: Nov 13, 2026 This Week in Cardiology
7
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis
New England Journal of Medicine· Watts G et al.
Nov 4
8
TAVR in Patients with Moderate Aortic Stenosis with At-Risk Features
New England Journal of Medicine· Généreux P et al.
Nov 2
300 likes12 news
EditorialPodcast
Coverage details
Editorial: NEJM
Podcast: Nov 06, 2026 This Week in Cardiology
9
Intensive Blood-Pressure Lowering in Patients with Type 2 Diabetes
New England Journal of Medicine· Santo K et al.
Nov 7
10
Extended Analyses of Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a)
NEJM Evidence· Nissen S et al.
Nov 7
11
Intensive Blood-Pressure Control in Patients with Previous Ischemic Stroke
New England Journal of Medicine· Silva G et al.
Nov 7
12
Statin–Ezetimibe Combination Therapy versus Statin Monotherapy in Atherosclerotic Cardiovascular Disease: A Prespecified Secondary Analysis of the Randomized Ez-PAVE Trial
Circulation· Lee S et al.
Nov 7
15
Cardiovascular Health Promotion for US Veterans: Current State, Gaps, and Strategies: A Scientific Statement From the American Heart Association
Circulation· Yuan N et al.
Nov 11
16
Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event
New England Journal of Medicine· Gibson C et al.
Aug 29
17
Effectiveness of Radiofrequency Renal Denervation in the United States: Six-Month Primary End Point Results From the SPYRAL AFFIRM Study
Circulation Cardiovascular Interventions· Kandzari D et al.
Nov 3
18
1-Year Safety and Effectiveness of a Next-Generation Dual-Seal Left Atrial Appendage Occluder
JACC: Cardiovascular Interventions· Lakkireddy D et al.
Nov 1
20
Percutaneous Transcatheter Mitral Valve Replacement for Symptomatic Mitral Regurgitation
Journal of the American College of Cardiology· Webb J et al.
Nov 1
21
Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation
Journal of the American College of Cardiology· Bikdeli B et al.
Nov 1
22
Early Increases in GDF-15 Are Associated With Declines in Cardiac Function With Breast Cancer Therapy
JACC Advances· Wilcox N et al.
Nov 1
Editorial
Coverage details
Editorial: ACC Journal Scan (X)
23
3-Year Comparison of Sirolimus- Versus Paclitaxel-Coated Balloon Angioplasty in Femoropopliteal Artery Disease
JACC: Cardiovascular Interventions· Teichgräber U et al.
Nov 1
Editorial
Coverage details
Editorial: ACC Journal Scan (X)
24
Prevalence of Silent Atherosclerosis across Adult Life
New England Journal of Medicine· Bundgaard H et al.
Aug 29
25
Multimodality Cardiac Imaging Substudy of the DAPT-SHOCK-AMI Randomized Trial: Echocardiographic and Cardiac Magnetic Resonance Assessment of Cangrelor versus Crushed Ticagrelor in Cardiogenic Shock Complicating Acute Myocardial Infarction
Circulation· Motovska Z et al.
Nov 7
26
Prehospital Extracorporeal Life Support in Refractory Out-of-Hospital Cardiac Arrest
New England Journal of Medicine· Miranda D et al.
Nov 7
27
Prasugrel versus Ticagrelor in Acute Coronary Syndromes
New England Journal of Medicine· Ömerovic E et al.
Aug 29
28
Intravenous Thrombolysis for Acute Ischemic Stroke — New Directions
New England Journal of Medicine· Grotta J et al.
Nov 4
29
Immediate Ambulatory Electrocardiographic Monitoring in Syncope
New England Journal of Medicine· Reed M et al.
Aug 30
10 likes10 news
EditorialPodcast
Coverage details
Editorial: NEJM
Podcast: Oct 30 2026 This Week in Cardiology
30
Hemodynamic effects of semaglutide in individuals with heart failure with preserved ejection fraction and obesity: a placebo-controlled randomized clinical trial
Nature Medicine· Borlaug B et al.
Nov 8
31 likes4 news
31
Single vs Double ProGlide Devices for Access Site Closure after Transfemoral Aortic Valve Replacement
Journal of the American College of Cardiology· Liu X et al.
Nov 1
32
Transcatheter Aortic Valve Replacement in Pure Aortic Regurgitation: The Randomized SEASON-AR Clinical Trial
Circulation· Gao X et al.
Oct 31
54 likes3 news
33
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis
New England Journal of Medicine· Bundgaard H et al.
Aug 28
47 likes7 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan (X)
Podcast: Oct 02 2026 This Week in Cardiology
34
Moderate Aortic Stenosis with At-Risk Features
Journal of the American College of Cardiology· Généreux P et al.
Nov 1
35
Efficacy and Safety of Routine Postdilation in Balloon-Expandable Transcatheter Aortic Valve Implantation Platform
JAMA Cardiology· Autherith M et al.
Nov 3
36
Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells
Nature Cardiovascular Research· Solomonidis E et al.
Nov 3
1 news
37
Discontinuing Statins in Older Adults without Cardiovascular Disease
New England Journal of Medicine· Rodondi N et al.
Nov 7
26 likes2 news
38
Cardiovascular outcomes with survodutide in adults with obesity at increased cardiovascular risk (SYNCHRONIZE-CVOT): a double-blind, randomised, placebo-controlled, phase 3 trial
The Lancet· Bozkurt B et al.
Nov 1
34 likes8 news
40
Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain
New England Journal of Medicine· Lee K et al.
Aug 29
55 likes7 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan
Podcast: Sep 11 2026 This Week in Cardiology
41
Iron Repletion in Heart Failure With Preserved Ejection Fraction: The IRONMET-HFpEF Randomized Trial
Circulation· Lewis G et al.
Nov 8
29 likes8 news
42
Selective blockade of microRNA-31-5p−calcitonin receptor interaction reverses established atrial fibrosis and atrial arrhythmia burden
Nature Cardiovascular Research· Trompf* J et al.
Oct 30
9 news
43
10-Year Outcomes of Initial CTO-PCI Versus No CTO-PCI Strategies for Chronic Total Occlusion: The DECISION-CTO Randomized Trial
Journal of the American College of Cardiology· Kim J et al.
Nov 1
Podcast
Coverage details
Podcast: Nov 06, 2026 This Week in Cardiology
44
Nov 5
Editorial
Coverage details
Editorial: AHA Professional Heart Daily
45
Heart failure therapy in congenitally corrected transposition of the great arteries: effect on right ventricular function and survival
European Heart Journal· Ahmed S et al.
Nov 4
Editorial
Coverage details
Editorial: European Heart Journal
46
Comparative Efficacy and Safety of Four Novel Monoclonal Antibody PCSK9 Inhibitors: A Bayesian Network Meta‐Analysis of Lipid and Safety Outcomes
Journal of the American Heart Association· Warraich K et al.
Nov 10
47
Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials
The Lancet· Boeddinghaus J et al.
Oct 1
48
Abstract 14941: Efficacy and Safety of Factor XIa Inhibitors for Secondary Prevention of Noncardioembolic Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Circulation· Ejaz A et al.
Nov 2
Editorial
Coverage details
Editorial: Circulation
49
Left Atrial Appendage Closure in Patients Considered Unsuitable for Oral Anticoagulation
Journal of the American College of Cardiology· Reddy V et al.
Nov 1
5 news
Editorial
Coverage details
Editorial: ACC Journal Scan
50
Remote Voice Analysis for Monitoring Ambulatory Heart Failure Patients: Results of the DETECT-HF Study
JACC Heart Failure· Abraham W et al.
Nov 1
6 news
Editorial
Coverage details
Editorial: ACC Journal Scan
Evidence-backed clinical questions
- Does sglt2 inhibitors vs dpp-4 inhibitors improve All-Cause Hospitalization in Diabetes Mellitus, Type 2? — 2 studies (35,860 patients) provide low-certainty evidence for benefit of sglt2 inhibitors for All-Cause Hospitalization in Diabetes Mellitus, Type 2.
- Does asparaginase vs placebo improve outcomes in L2 Acute Lymphoblastic Leukemia? — 4 studies (221 patients) provide low-certainty evidence against benefit of asparaginase for Myocardial Infarction Hospitalization in L2 Acute Lymphoblastic Leukemia.
- Does phenylephrine vs placebo improve Systolic Blood Pressure? — 2 studies (45 patients) provide low-certainty evidence against benefit of phenylephrine for Systolic Blood Pressure in this population.
- Does amiodarone vs placebo improve outcomes in Atrial Fibrillation? — 60 studies (461,152 patients, 7 RCTs) provide moderate-certainty evidence against benefit of amiodarone for Myocardial Infarction Hospitalization in Atrial Fibrillation.