PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 29, 20260 citationsOpen Access

Scaling up YFV 17DD virus to a 40-liter pilot-scale stirred-tank bioreactor at Bio-Manguinhos Pilot Plant

View Full Paper
APAdrian PenhaANAna NevesCSClara Santos

Key Points

  • The goal is to explore the production efficiency of YFV 17DD virus in a larger bioreactor setting.
  • Utilized a 40-liter stirred-tank bioreactor for scaling up the virus production.
  • Conducted within the Bio-Manguinhos Pilot Plant facilities.
  • Presented at the International Symposium on Immunobiologicals.
  • Successful implementation of the bioreactor scale-up process.
  • Potential improvements in the yield and efficiency of YFV 17DD virus production.
  • Highlights the advancements in biomanufacturing for vaccine development.

Abstract

Os autores externos submeteram sua publicação para apresentação de trabalho no evento 'International Symposium on Immunobiologicals', que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Penha et al. (2026) studied this question.

synapsesocial.com/papers/6a192c45fab5b468c4415360https://doi.org/10.35259/isi.2026_76346
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Scale-up of plasmid linearization for mRNA vaccine production: from development to pilot scale2026
  2. 2A cell-based technological proposal for modernization and optimization of the 17DD yellow fever vaccine production2026
  3. 3Bio-Manguinhos and new generation of vaccines: consolidation of mRNA-LNP production and evaluation of critical quality attributes at pilot scale2026
  4. 4Evaluation of the doubling of production capacity for the Mumps API using roller bottles2026
  5. 5Sanitization protocol for bioburden control in complexes equipment of biopharmaceutical production2026