Surgical resection of primary cardiac tumors resulted in long-term survival up to 15 years that was comparable to the age- and sex-matched general population (relative survival 0.91).
Observational (n=60)
No
Does surgical resection improve long-term survival in patients with primary cardiac tumors compared to the general population?
Surgical resection of benign primary cardiac tumors yields excellent long-term survival comparable to the general population, whereas malignant tumors have a poor prognosis.
Effect estimate: relative survival 0.91 (95% CI 0.68-1.23)
Introduction: Primary cardiac tumors are a rare condition presenting with a variety of symptoms. The outcomes of their surgical treatment in the modern era from central Europe have not been recently reported. Aim: To evaluate the short-and long-term outcomes of the cardiac tumor operations at our department throughout the last 20 years. Material and methods: This was a retrospective analysis of all primary cardiac tumor operations performed at our institution between 2000 and 2020. Perioperative data were extracted from patient records. Long-term data were provided by the National Registry of Cardiac Surgery. Results: Sixty procedures for primary cardiac tumor were performed throughout the study period. The most common type of tumor was myxoma (88%), followed by fibroelastoma (8%), lipoma (2%) and sarcoma (2%). There were 2 perioperative deaths (3%). The most common perioperative complication was atrial fibrillation (47%). One (2%) patient underwent reoperation 6 years later because of myxoma recurrence. We recorded 13 long-term deaths, but only 1 patient died as a consequence of cardiac tumor (sarcoma) 15 months after the surgery. Long-term survival of the cohort was comparable with the age-and sexmatched general population up to 15 years postoperatively (relative survival 0.91, CI 0.68-1.23). Rich histopathological illustrations are provided in the online supplementary material. Conclusions: Surgical resection is the standard treatment of primary cardiac tumors. The outcomes of benign tumors are excellent and the long-term postoperative survival is comparable with the general population. The prognosis of malignant tumors remains poor.
Děrgel et al. (Sat,) conducted a observational in Primary cardiac tumors (n=60). Surgical resection vs. Age- and sex-matched general population was evaluated on Long-term relative survival at 15 years (relative survival 0.91, 95% CI 0.68-1.23). Surgical resection of primary cardiac tumors resulted in long-term survival up to 15 years that was comparable to the age- and sex-matched general population (relative survival 0.91).
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